How Does Cerenia Kill a Dog? Everything You Need To Know

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If your dog suffers from vomiting or motion sickness, you may have heard of Cerenia, a medication that can help control these symptoms. But what is Cerenia, how does it work, and what are the possible side effects?

And more importantly, can Cerenia kill your dog if given incorrectly or overdosed?

Dog Vomiting

In this blog post, we will answer these questions and more, so you can make an informed decision about using Cerenia for your dog.

What is Cerenia?

Cerenia is the brand name of maropitant citrate, a drug used to treat vomiting in dogs and cats. In dogs, it’s also used to prevent vomiting due to motion sickness.

Cerenia can also prevent vomiting that occurs as a side effect of anesthesia and other medications, such as chemotherapy.[1] A veterinarian will need to prescribe Cerenia for your pup.

How Cerenia Works

How Cerenia Works?

Cerenia plays the role by preventing substance P from acting in the brain and digestive system. When the body detects a problem, substance P is involved in causing the vomiting reflex to occur.

The active substance of Cerenia is maropitant, a neurokinin-1 (NK1) receptor antagonist, which acts in the central nervous system by inhibiting Substance P, the key neurotransmitter involved in vomiting. By inhibiting substance P, maropitant acts as an anti-emetic.

Cerenia can cease or reduce dog vomiting by decreasing substance P. [2]

Side Effects of Cerenia

According to PetMD, Most dogs normally handle cerenia well, but like any drug, it might have some undesirable consequences. The most typical negative effects of Cerenia include:

  • Lethargy
  • Diarrhea
  • Drooling
  • Appetite loss
  • Injection site reactions (if given by injection)

These side effects are usually mild and temporary, and should go away once the medication is stopped. However, if they persist or worsen, you should contact your veterinarian.

Excessive Drooling

Precautions You Must Know

According to Dailymed, If your dog has any medical disorders prior to receiving Cerenia, especially liver issues as Cerenia is processed by the liver, you should let your veterinarian know.

If your dog is expecting, nursing, or taking any other drugs or supplements, you should also let your vet know.

While administering Cerenia to your dog, make sure to carefully follow your veterinarian’s recommendations. Never provide the medication in excess or insufficiently, or more often than advised.

If you forget to take a dosage, take it as soon as you recall unless the following dose is practically due. Never provide two doses at once.

You should monitor your dog’s condition after giving Cerenia and report any unusual signs or symptoms to your veterinarian. Some signs of overdose or adverse reaction include:

  • Excessive drooling
  • Tremors
  • Seizures
  • Difficulty breathing
  • Collapse
  • Death

If you notice any of these signs, seek emergency veterinary care immediately.

Can Cerenia Kill a Dog?

  • Cerenia is a safe and effective medication for most dogs when used as directed by a veterinarian. However, if given incorrectly or overdosed, Cerenia can be fatal for dogs.
  • There have been reports of dogs dying or suffering serious complications after receiving Cerenia, either by accidental ingestion, incorrect dosage, or inappropriate administration.
  • For example, one case report described a 10-year-old Labrador retriever that died after receiving an intravenous injection of Cerenia instead of an intramuscular injection as prescribed.
  • The dog developed severe respiratory distress and cardiac arrest within minutes of the injection.
  • Another case report described a 6-year-old mixed-breed dog that died after ingesting 20 tablets of Cerenia meant for another dog. The dog showed signs of severe neurological toxicity and was euthanized.
  • A third case report described a 4-year-old golden retriever that developed acute kidney injury after receiving an overdose of Cerenia by injection. The dog recovered after intensive treatment.
  • Always keep Cerenia out of reach of children and pets, and never give it to your dog without consulting your veterinarian.

How Long Does Cerenia Last in Dogs?

A medication called Cerenia helps treat nausea and vomiting[3] in dogs. Both an injection and a pill are available. How long the medication works for your dog may depend on the form you choose. Observe the following crucial information:

1) Cerenia via Injection: Your dog will often receive this version of Cerenia from a veterinarian. It is useful in emergencies or when your dog is unable to ingest medicines since it works quickly.

For up to 24 hours after the injection, nausea and vomiting are prevented.

2) Cerenia via Tablet: This version of Cerenia may be administered to your dog at home. Moreover, it can stop nausea and vomiting for up to a day.

It should be administered to your dog once daily, or as directed by your veterinarian.Be aware that every dog may respond to the medication differently.

The speed at which your dog breaks down the medication, the state of his or her health, and the nature of the nausea and vomiting all may have an impact.

Hence, once your veterinarian prescribes Cerenia for your dog, you should always go by what they advise.

Moreover, be aware that dogs that take Cerenia may experience certain adverse effects, such as drowsiness, lack of appetite, or loose feces.

See your veterinarian immediately away if you notice any of these symptoms or if your dog’s condition worsens or does not improve.

This material is not intended to take the place of veterinary professionals’ advice. Always inquire with your vet about the precise condition and course of treatment for your dog.

Alternatives to Cerenia for Dogs

If you’re exploring alternatives to Cerenia for your dog’s vomiting or motion sickness, it’s important to consult your veterinarian before trying any new treatments.

However, there are some natural remedies and other medications that may help alleviate these symptoms. Here are a few options:

Natural Remedies:

1) Ginger: Ginger has anti-inflammatory and anti-nausea properties. You can give your dog ginger in various forms, such as fresh root, powder, capsules, tea, or biscuits.

The recommended dose is 50 mg per kg of body weight per day.

2) Chamomile: Chamomile has soothing effects on the digestive system. You can give your dog chamomile tea or capsules.

The recommended dose is 1 mg per kg of body weight per day.

Chamomile Tea For Dogs Medication

3) Peppermint: Peppermint has antispasmodic and carminative effects on the stomach and intestines. You can give your dog peppermint oil or leaves.

The recommended dose is 0.1 to 0.25 ml per kg of body weight per day.

4) Pumpkin: Pumpkin[4] has high fiber content and can help regulate bowel movements. You can give your dog canned pumpkin (not pie filling) or fresh cooked pumpkin.

The recommended dose is 1 teaspoon per 10 pounds of body weight per day.

Medication Options:

1) Meclizine: Meclizine is an antihistamine that can prevent motion sickness-induced nausea and vomiting in dogs.

It is available over-the-counter as Dramamine Less Drowsy Formula or Bonine. The recommended dose is 25 mg per dog once daily.

2) Diphenhydramine: Diphenhydramine is an antihistamine that can help with motion sickness-related symptoms.

It is available over-the-counter as Benadryl or generic brands. The recommended dose is 1 mg per pound of body weight every 8 hours.

3) Ondansetron: Ondansetron is an antiemetic used to prevent nausea and vomiting caused by chemotherapy or other medications in dogs.

It requires a prescription and is available as Zofran or generic brands. The recommended dose is 0.5 to 1 mg per kg of body weight every 12 hours.

Remember, it’s crucial to consult your veterinarian to determine the most suitable alternative treatment for your dog, considering their specific condition, medical history, and individual needs.

FAQs

Can cerenia hurt a dog?

Cerenia can hurt a dog if given incorrectly or overdosed. Some signs of overdose or adverse reaction include excessive drooling, tremors, seizures, difficulty breathing, collapse, and death. If you notice any of these signs, seek emergency veterinary care immediately.

Does cerenia make your pet sleepy?

Yes, Cerenia can cause drowsiness in pets as a side effect, especially at higher doses or when given intravenously. However, the level of balance can vary between individuals. If you observe excessive sleepiness or any concerning side effects, consult your veterinarian.

Can dog eat after taking Cerenia?

If your dog is taking Cerenia for prevention of vomiting due to motion sickness, you should fast your dog for one hour before giving the medication. You should also avoid feeding your dog during travel or immediately after arrival at the destination.

How many days can a dog take Cerenia?

You can give your dog Cerenia tablets once a day for up to five days in a row to prevent acute vomiting and for motion sickness, you can give cerenia tablets once a day for up to two consecutive days.

How does cerenia make dogs constipated?

Cerenia rarely causes constipation in dogs, although its exact mechanism is unclear. If constipation occurs, consult a veterinarian for guidance. Measures such as increased hydration, dietary adjustments, or stool softeners may be recommended. Other factors can contribute to constipation, so professional evaluation is crucial.

Conclusion

It is important to make it clear that Cerenia is a safe and effective drug for dogs when taken as directed and per a veterinarian’s prescription. It can be frightful to talk about how Cerenia might hurt a dog, though.

Instead, let’s emphasize the significance of giving pets proper care and seeking competent advice. You can make sure your beloved dog is healthy by working closely with your veterinarian and according to their recommendations.

Keep in mind that knowledge and proper care are the keys to keeping your dog safe, healthy, and happy. Let’s band together to provide a safe and caring environment for our beloved dogs!

Reference:

  1. MacDonald, V. (2009, June 1). Chemotherapy: Managing side effects and safe handling. PubMed Central (PMC). Retrieved May 30, 2023, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684058/- PubMed
  2. Motion Sickness in Dogs. (n.d.). Vca Hospitals. Retrieved May 30, 2023, from https://vcahospitals.com/know-your-pet/motion-sickness-in-dogs- VCA
  3. Vomiting. (2023, May 5). Cornell University College of Veterinary Medicine. Retrieved May 30, 2023, from https://www.vet.cornell.edu/departments-centers-and-institutes/riney-canine-health-center/health-info/vomiting- Cornell University
  4. Burke, A. (2022). ​Can Pumpkin Help With Dog Diarrhea? American Kennel Club. https://www.akc.org/expert-advice/health/can-pumpkin-help-with-dog-diarrhea/- AKC